Story:

Cleft Gene Test

Writer:

Sara Ivey

972-572-4839

Script #

580

Photographer:

Pat Broyles

Project:

Dental Health Check

Shoot date:

9/8/04

AIRDATE:

Monday, Nov. 1, 2004

DHC Master

#20

Broadcasts:

Daybreak and Midday

Timecode:

16:05

Pkg Length:

1:38

VIDEO

AUDIO

ANCHOR LEAD IN

ANCHOR:

Researchers are isolating the genetic markers that increase the risk of a common birth defect: cleft lip and palate. Dr. Linda Niessen looks at the latest findings and what they mean to women planning to get pregnant. Here is today's dental health check.

GENETIC LAB RESEARCH

(VOICEOVER):

A new genetic test can screen for about 15 percent of cases of cleft lip and palate.

NEW BORN BABY WITH DEFECT

One in every 600 babies in the u.s. is born with a cleft defect and no other problems. These cases are called isolated and are not associated with other birth defects.

SUPER:

DR. LYNNE OPPERMAN

BAYLOR COLLEGE OF DENTISTRY

:19-24

“What they’ve identified is a marker gene that obviously piggy backs along with whatever the mutated gene is.”

DR. OPPERMAN WITH DR. NIESSEN

Dr. Lynne Opperman at Baylor College of Dentistry studies genetic defects and how the human face and skull develops before birth.

DR. OPPERMAN

“Plan your family. In order words, decide when you want to get pregnant.”

PREGNANT PATIENT WALKING INTO OFFICE

Dr. Opperman says women who plan to get pregnant should focus on factors they can control, not genetics.

Dr. Opperman

“When you decide you want to get pregnant, stop all those bad habits you have. Stop smoking. Stop drinking.”

DRAWINGS OF FACIAL DEVELOPMENT

The cleft lip or palate defect occurs within the first eight weeks of fetal development.

DR. OPPERMAN

MORE PHOTOS OF 7 WEEK/8 WEEK FETAL DEVELOPMENT

“And the problem is that the face develops so early on that by the time you find out that you are pregnant, your baby already has a face. And any anomalies that are associated with your bad habits have already happened.”)

PRENATAL VITAMINS WITH FOLIC ACID

Eat a healthy diet. Take prenatal vitamins with folic acid.

HEALTHY BABY

“You can prevent birth defects by living a healthy lifestyle.”

ON CAMERA

Dr. Niessen:

SUPER:

DR. LINDA NIESSEN BAYLOR COLLEGE OF DENTISTRY

1:19-1:24

While science continues to unravel the mystery of cleft lip and palate, the lifestyle cause are well known. So before getting pregnant, you should stop smoking and drinking. Your baby's face depends upon it. for Baylor College of Dentistry, Texas A&M system, I’m Dr. Linda Niessen, Channel 8 news.